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Beilstein J. Org. Chem. 2018, 14, 576–582, doi:10.3762/bjoc.14.44
Graphical Abstract
Scheme 1: Synthesis of chiral α-fluoroalkylated tertiary alcohols.
Scheme 2: Scope of fluoroalkylated pyruvates. Yields were determined by 19F NMR analysis using benzotrifluori...
Scheme 3: Catalytic asymmetric methylation of the simple perfluoroalkylated ketone 3a. Yields were determined...